General Pediatrics

Clarithromycin is useful for the treatment of: Upper respiratory tract infections (tonsillitis, pharyngitis, sinusitis, otitis). Lower respiratory tract infections (bronchitis, pneumonia). Therapeutic indications for Clarithromycin: - Oral, in immediate-release and modified-release formulations: Adults and children ≥12 years: pharyngitis, tonsillitis, sinusitis (diagnosed), acute bronchitis, acute exacerbation of chronic bronchitis, bacterial pneumonia (community-acquired), mild-to-moderate skin and soft tissue infections, folliculitis, cellulitis, erysipelas. - Oral, in immediate-release formulations: Adults and children ≥12 years: localized or disseminated infection caused by M. avium or M. intracellulare, localized infection caused by M. chelonae, M. fortuitum, and M. kansaii. Gastric or duodenal ulcer associated with H. pylori (in conjunction with appropriate anti-ulcer medication). Prevention of disseminated M. avium complex infection in high-risk HIV patients (CD4 lymphocytes ≤ 50/mm³). Children > 12 months to 11 years: streptococcal pharyngitis, bacterial bronchitis and pneumonia, acute otitis media, impetigo, folliculitis, cellulitis, abscesses. - IV: Adults: parenteral treatment of streptococcal pharyngitis or tonsillitis if first-line treatment with beta-lactams is not possible or there is demonstrated susceptibility to S. pyogenes; diagnosed acute bacterial sinusitis; acute exacerbation of chronic bronchitis; mild-to-moderate skin and soft tissue infections if beta-lactams are not appropriate.